Latest insider trades

P = PurchaseS = SaleM = Option exerciseA = Award/GrantF = Tax withholdingG = Gift

• EVNIN LUKEsold41,287 shares ofHOWLat $0.83$34KNov 25Details
• EVNIN LUKEsold56,992 shares ofHOWLat $0.98$56KNov 25Details
• EVNIN LUKEsold27,297 shares ofHOWLat $0.92$25KNov 25Details
• MPM BioVentures 2014, L.P.sold64,331 shares ofHOWLat $0.83$53KNov 25Details
• MPM BioVentures 2014, L.P.sold88,802 shares ofHOWLat $0.98$87KNov 25Details
• MPM BioVentures 2014, L.P.sold42,533 shares ofHOWLat $0.92$39KNov 25Details
• GADICKE ANSBERTsold52,627 shares ofHOWLat $0.93$49KNov 20Details
• GADICKE ANSBERTsold66,324 shares ofHOWLat $0.94$62KNov 20Details
• GADICKE ANSBERTsold41,152 shares ofHOWLat $0.89$37KNov 20Details
• EVNIN LUKEsold33,776 shares ofHOWLat $0.93$31KNov 20Details
• EVNIN LUKEsold42,566 shares ofHOWLat $0.94$40KNov 20Details
• EVNIN LUKEsold26,411 shares ofHOWLat $0.89$24KNov 20Details
• MPM BioVentures 2014, L.P.sold52,627 shares ofHOWLat $0.93$49KNov 20Details
• MPM BioVentures 2014, L.P.sold66,324 shares ofHOWLat $0.94$62KNov 20Details
• MPM BioVentures 2014, L.P.sold41,152 shares ofHOWLat $0.89$37KNov 20Details
• GADICKE ANSBERTsold90,951 shares ofHOWLat $0.98$89KNov 17Details
• GADICKE ANSBERTsold61,640 shares ofHOWLat $0.93$57KNov 17Details
• GADICKE ANSBERTsold57,061 shares ofHOWLat $0.95$54KNov 17Details
• EVNIN LUKEsold58,372 shares ofHOWLat $0.98$57KNov 17Details
• EVNIN LUKEsold39,560 shares ofHOWLat $0.93$37KNov 17Details
• EVNIN LUKEsold36,621 shares ofHOWLat $0.95$35KNov 17Details
• MPM BioVentures 2014, L.P.sold90,951 shares ofHOWLat $0.98$89KNov 17Details
• MPM BioVentures 2014, L.P.sold61,640 shares ofHOWLat $0.93$57KNov 17Details
• MPM BioVentures 2014, L.P.sold57,061 shares ofHOWLat $0.95$54KNov 17Details
• GADICKE ANSBERTsold68,480 shares ofHOWLat $1.11$76KNov 12Details
• GADICKE ANSBERTsold48,570 shares ofHOWLat $1.18$57KNov 12Details
• GADICKE ANSBERTsold55,810 shares ofHOWLat $1.14$64KNov 12Details
• GADICKE ANSBERTsold40,669 shares ofHOWLat $1.09$44KNov 12Details
• EVNIN LUKEsold43,950 shares ofHOWLat $1.11$49KNov 12Details
• EVNIN LUKEsold31,172 shares ofHOWLat $1.18$37KNov 12Details
• EVNIN LUKEsold35,818 shares ofHOWLat $1.14$41KNov 12Details
• EVNIN LUKEsold26,101 shares ofHOWLat $1.09$28KNov 12Details
• MPM BioVentures 2014, L.P.sold68,480 shares ofHOWLat $1.11$76KNov 12Details
• MPM BioVentures 2014, L.P.sold48,570 shares ofHOWLat $1.18$57KNov 12Details
• MPM BioVentures 2014, L.P.sold55,810 shares ofHOWLat $1.14$64KNov 12Details
• MPM BioVentures 2014, L.P.sold40,669 shares ofHOWLat $1.09$44KNov 12Details
• GADICKE ANSBERTsold140,488 shares ofHOWLat $1.22$171KNov 6Details
• GADICKE ANSBERTsold47,950 shares ofHOWLat $1.22$58KNov 6Details
• GADICKE ANSBERTsold54,452 shares ofHOWLat $1.21$66KNov 6Details
• EVNIN LUKEsold90,164 shares ofHOWLat $1.22$110KNov 6Details
• EVNIN LUKEsold30,774 shares ofHOWLat $1.22$38KNov 6Details
• EVNIN LUKEsold34,947 shares ofHOWLat $1.21$42KNov 6Details
• MPM BioVentures 2014, L.P.sold140,488 shares ofHOWLat $1.22$171KNov 6Details
• MPM BioVentures 2014, L.P.sold47,950 shares ofHOWLat $1.22$58KNov 6Details
• MPM BioVentures 2014, L.P.sold54,452 shares ofHOWLat $1.21$66KNov 6Details
• GADICKE ANSBERTsold86,936 shares ofHOWLat $1.43$124KNov 3Details
• GADICKE ANSBERTsold114,044 shares ofHOWLat $1.28$146KNov 3Details
• GADICKE ANSBERTsold94,063 shares ofHOWLat $1.29$121KNov 3Details
• EVNIN LUKEsold55,795 shares ofHOWLat $1.43$80KNov 3Details
• EVNIN LUKEsold73,192 shares ofHOWLat $1.28$94KNov 3Details