Latest insider trades

P = PurchaseS = SaleM = Option exerciseA = Award/GrantF = Tax withholdingG = Gift

• EVNIN LUKEsold60,369 shares ofHOWLat $1.29$78KNov 3Details
• MPM BioVentures 2014, L.P.sold86,936 shares ofHOWLat $1.43$124KNov 3Details
• MPM BioVentures 2014, L.P.sold114,044 shares ofHOWLat $1.28$146KNov 3Details
• MPM BioVentures 2014, L.P.sold94,063 shares ofHOWLat $1.29$121KNov 3Details
• GADICKE ANSBERTsold72,709 shares ofHOWLat $1.72$125KOct 29Details
• GADICKE ANSBERTsold69,068 shares ofHOWLat $1.64$113KOct 29Details
• GADICKE ANSBERTsold134,240 shares ofHOWLat $1.55$208KOct 29Details
• EVNIN LUKEsold46,664 shares ofHOWLat $1.72$80KOct 29Details
• EVNIN LUKEsold44,327 shares ofHOWLat $1.64$73KOct 29Details
• EVNIN LUKEsold86,154 shares ofHOWLat $1.55$134KOct 29Details
• MPM BioVentures 2014, L.P.sold72,709 shares ofHOWLat $1.72$125KOct 29Details
• MPM BioVentures 2014, L.P.sold69,068 shares ofHOWLat $1.64$113KOct 29Details
• MPM BioVentures 2014, L.P.sold134,240 shares ofHOWLat $1.55$208KOct 29Details
• HICKLIN DANIEL Jgranted435,000 shares ofHOWLat $0Jan 4Details
• Seidel-Dugan Cynthiagranted150,000 shares ofHOWLat $0Jan 4Details
• Karunatilake Chulanigranted150,000 shares ofHOWLat $0Jan 4Details
• Isaacs Randigranted200,000 shares ofHOWLat $0Jan 4Details
• Lubman Ellengranted131,900 shares ofHOWLat $0Jan 4Details
• Trost Timothy W.granted150,000 shares ofHOWLat $0Jan 4Details
• Atkins Michael B.granted35,000 shares ofHOWLat $0Jan 4Details