Latest insider trades

P = PurchaseS = SaleM = Option exerciseA = Award/GrantF = Tax withholdingG = Gift

• Novo Holdings A/Sbought555,555 shares ofAVLNat $18$10MMay 5Details
• FMR LLCtraded377,948 shares ofAVLNMay 5Details
• FMR LLCtraded225,843 shares ofAVLNMay 5Details
• FMR LLCtraded872,868 shares ofAVLNMay 5Details
• FMR LLCtraded80,291 shares ofAVLNMay 5Details
• FMR LLCtraded727,585 shares ofAVLNMay 5Details
• Novo Holdings A/Straded3,327,734 shares ofAVLNMay 5Details
• Novo Holdings A/Straded12,558,081 shares ofAVLNat $0May 5Details
• Novo Holdings A/Straded5,587,603 shares ofAVLNat $0May 5Details
• Novo Holdings A/Straded25,899,284 shares ofAVLNat $0May 5Details
• Novo Holdings A/Straded1,986,369 shares ofAVLNat $0May 5Details
• Novo Holdings A/Straded18,000,000 shares ofAVLNat $0May 5Details
• Golden Adam H.granted254,891 shares ofAVLNat $0May 4Details
• Carroll Jilltraded9,418,561 shares ofAVLNMay 1Details
• Carroll Jilltraded27,309,719 shares ofAVLNMay 1Details
• Carroll Jillbought277,778 shares ofAVLNat $18$5MMay 1Details
• Carroll Jilltraded489,486 shares ofAVLNMay 1Details
• Carroll Jilltraded1,419,298 shares ofAVLNMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCtraded9,418,560 shares ofAVLNMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCtraded6,827,429 shares ofAVLNMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCtraded9,418,561 shares ofAVLNMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCtraded27,309,719 shares ofAVLNMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCbought277,777 shares ofAVLNat $18$5MMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCtraded354,824 shares ofAVLNMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCbought277,778 shares ofAVLNat $18$5MMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCtraded489,486 shares ofAVLNMay 1Details
• SR ONE CAPITAL MANAGEMENT, LLCtraded1,419,298 shares ofAVLNMay 1Details
• Congleton Jongranted26,978 shares ofAVLNat $0May 1Details
• Rhodes Melissagranted211,975 shares ofAVLNat $0May 1Details
• Carlson Douglas Rgranted211,975 shares ofAVLNat $0May 1Details
• Haviland Kategranted26,978 shares ofAVLNat $0May 1Details
• Wellington Biomedical Innovation Master Investors (Cayman) II L.P.traded4,060,259 shares ofAVLNat $0May 1Details
• Wellington Biomedical Innovation Master Investors (Cayman) II L.P.traded20,482,289 shares ofAVLNat $0May 1Details
• Wellington Biomedical Innovation Master Investors (Cayman) II L.P.traded1,275,486 shares ofAVLNMay 1Details
• Lazarus Howardgranted211,975 shares ofAVLNat $0May 1Details
• Lavelle Eringranted26,978 shares ofAVLNat $0May 1Details
• Baranowski Lyngranted501,033 shares ofAVLNat $0May 1Details
• Turner Heather Dgranted26,978 shares ofAVLNat $0May 1Details