Suvretta Capital Management has been a consistent accumulator of shares across its two reported holdings, with Form 4 filings showing 37 transactions totaling roughly $44.7 million in purchases and zero sales. The firm’s recent activity is heavily concentrated in MANE, where it executed 23 open-market buys between February 4 and February 6, 2026, ranging from $58,910 to nearly $2 million per transaction. Those purchases, which included multiple same-day executions, pushed the total buy value for the period to roughly $10.6 million. The firm also added to its position in BNTC with four open-market purchases in late December 2025, valued between $32,959 and $884,352.
The pattern is unambiguous: Suvretta is building positions, not trimming them. The only non-purchase transactions in the recent window were two grants of MANE shares on May 1, 2026, valued at roughly $15.1 million and $14.9 million, respectively. Those are compensation-related awards, not discretionary trades, and they do not alter the directional signal from the open-market activity. Across all filings, the firm reported $29.99 million in acquired value from grants and exercises, but the $44.68 million in open-market purchases—with no corresponding sales—shows a clear accumulation bias.
The concentration in MANE is notable, with the firm layering in shares across multiple price points over a three-day span in early February. The BNTC purchases, while smaller in aggregate, followed the same pattern of steady accumulation. With no sell transactions reported in any of the 37 filings, Suvretta’s recent Form 4 history reflects a firm that is adding to existing positions rather than rotating out of them.
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